ACIST Enters Co-Promotion Agreement with Medtronic to Commercialize Next-Generation FFR and IVUS Technologies in U.S.

Collaboration provides increased commercial reach, brand synergies and customer access to new technologies
EDEN PRAIRIE, Minn. (August 4, 2014) – ACIST Medical Systems, Inc., a Bracco Group company offering advanced contrast delivery systems for cardiology, today announced that it has
entered into a strategic agreement with Medtronic, Inc. to co-promote the world’s first Rapid Exchange Fractional Flow Reserve (FFR) (RXi) and High Definition Intravascular Ultrasound (IVUS) (HDi) technologies in the United States. Under this
agreement, ACIST and Medtronic will work collaboratively to introduce these groundbreaking products into cardiac catheterization laboratories across the US.

The ACIST Rapid FFR (RXi) and High Definition IVUS (HDi) systems are quicker, easier to use and offer detailed insight that physicians can use to optimize treatment choice for their patients.
ACIST’s new Rapid FFR system, which utilizes the ultra-thin ACIST Navvus™ Rapid Exchange
MicroCatheter and RXi console, was introduced earlier this year in the United States and Europe. The Navvus MicroCatheter can be used over a standard 0.014 inch guidewire, and the RXi system facilitates rapid FFR assessments before, during and post-intervention.