Issue Highlights

Pharmacotherapeutics
Think of the P2Y12 receptor as being shaped like a crown. If you drop a ball into the central part of the crown, that is the ADP site of the receptor. Clopidogrel, prasugrel, and cangrelor occupy…
You have a long interest in antiplatelet therapy. When did it start? My interest in antiplatelet therapy began far back in the 1980s when I was a co-investigator in a trial utilizing ticlopidine (Ticlid) as an anti-restenotic agent for plain old balloon angioplasty (POBA…